חזרה

פרופ' קריב רויטל

תפקידים ומקום עבודה:

רופאה בכירה במכון הגסטרו במרכז הרפואי איכילוב - בתחום הגסטרו והממאירויות מנהלת תחום הגסטרו במכבי שירותי בריאות 
משמשת כפרופסור חבר במסלול הרגיל באוניברסיטת תל אביב, חברת המועצה הלאומית לגסטרואנטרולוגיה, תזונה ומחלות כבד ופעילה בחוג לממאירויות של איגוד הגסטרואנטרולוגיה הישראלי.

התמחות ראשית:

גסטרואנטרולוגיה כללית
אונקולוגיה של מערכת העיכול - כולל גידולים ממאירים ונגעים טרום ממאירים של מערכת העיכול, גנטיקה של גידולים ממאירים ותורשה הקשורה לממאירות וכן מניעת גידולים במערכת העיכול

התמחות משנה:

רפואה פנימית

סוגי ניתוחים:

  • קולונוסקופיה
  • גסטרוסקופיה
  • סגמואידוסקופיה
  • כריתת פוליפים, הערכת עומס פוליפים (במקרים של ריבוי פוליפים)

הסדר עם חברות ביטוח וקופות:

הראל, מגדל, מנורה, כלל, איילון

השכלה:

בוגרת בית הספר לרפואה באוניברסיטה העברית, ירושלים
שרות צבאי כרופאה בעתודה האקדמי ת
התמחות ברפואה פנימית במרכז רפואי תל השומר
התמחות בגסטרואנטרולוגיה ומחלות כבד במרכז הרפואי סוראסקי תל אביב
התמחות בנושא גנטיקה של סרטן המעי הגס וכן סרטן ומחלות מעי דלקתיות בקליבלבד – אוניברסיטת Case ו - Cleveland clinic
ניהול השרות לממאירויות במרכז הרפואי סוראסקי 2007 - 2018 ניהול ארצי תחום גסטרו, מכבי שרותי בריאות מ 2012 – היום
השתלמות בגנומיקה וביואינפורמטיקה, אוניברסיטת בר אילן 2015 קורס מורים ליוגה
השתלמות בטיפול לבטן בשיטת יפנית - אנפוקו

ניסיון קליני:

מעקב לאחר אבחנת סרטן או פוליפים בדרכי העיכול, בעיקר בתחלואה בגיל צעיר
טיפול בתסמונות משפחתיות הגורמות לנטיה לפוליפים וגידולים במערכת העיכול
יעוץ לגבי מניעת גידולים סרטניים במערכת העיכול
ייעוץ טרום ניתוחי לאחר אבחנת סרטן המעי הגס
ייעוץ ואבחון גנטי לגבי גידולים ופוליפים במערכת העיכול. מתמחה בבדיקות Next Generation Sequencing ל - איתור שינויים תורשתיים הגורמים לסרטן בדרכי העיכול וההמלצות הנגזרות מאיתורם. בעיות במערכת העיכול לאחר טיפולים אונקולוגים וכירורגים
הפרעות במערכת העיכול לאחר תחלואה בסרטן וטיפולים קשורים הכוללים כמותרפיה, הקרנות וניתוחים המשפיעים על מערכת העיכול כגון – נזק קרינתי לרקטום, הפרעות ביציאות לאחר ניתוחים

פרופ’ קריב מטפלת בקשת הבעיות הקשורה למערכת העיכול
בירור רפואי, אבחון וטיפול כוללני בתסמינים (סימפטומים) שונים של מערכת העיכול
אי נוחות כללית וכאב במערכת העיכול העליונה או התחתונה, כאבי בטן, שינויים ביציאות – עצירות, שלשול, נפיחות, ירידת משקל, דמם ממערכת העיכול באתרים שונים ובירור של אנמיה. בירור של הפרעה בתפקודי הכבד וחסרים תזונתיים שונים טיפול בהפרעות ומחלות קיימות במערכת העיכול : מחלת ההחזר הושטי (רפלוקס), כיבים ודלקות בושט, קיבה ותרסריון, צליאק, מחלות מעי דלקתיות, תת ספיגה, מחלת
הסעיפים, בעיות בפי הטבעת (גישה רפואית ולא כירורגית), מעי רגיש, והפרעות תפקודיות של מערכת העיכול, בעיות במערכת העיכול הקשורות לאנדומטריוזיס.

חברות באיגודים:

פרופ ' קריב משמשת כרופאה בכירה בשרות לממאירויות במכון הגסטרו במרכז הרפואי תל אביב,
מנהלת תחום גסטרואנטרולוגיה ארצית של מכבי שרותי בריאות, פרופסור חבר במסלול הרגיל באוניברסיטת תל אביב, חברה המועצה הלאומית לגסטרואנטרולוגיה, תזונה ומחלות כבד ופעילה בחוג לממאירויות של איגוד הגסטרואנטרולוגיה הישראלי. כמו כן, חברה בארגונים מקצועיים ברחבי העולם ועוסקת במחקר בשיתוף עם אוניברסיטת ת”א, אוניברסיטת חיפה ומכון המחקר ע״ש מוריס קאהן של מכבי שרותי בריאות. פעילה ומרצה בכנסים ומפרסמת בעיתונות מקצועית

 

פרסומים

 

1. Kariv R(PI), Sidi Y(C), Gur H(C) .
Systemic vasculitis presenting as a tumorlike lesion. Four case reports and an analysis of 79 reported cases.
Medicine 2000 Nov;79(6): 349-59 .
(Impact Factor 4.233; Rank 17/151-Medicine, General and Internal). Citations (WOS):39

2. Kariv R(PI), Klempfner R(C), Barnea A(T), Sidi Y(C), Schwartz E(C) .
The changing epidemiology of leptospirosis in Israel .
Emerg Infect Dis 2001 Nov-Dec;7 (6):990-2.
(Impact Factor 5.993; Rank 17/135-Immunology;Rank 4/69-Infectious Diseases). Citations (WOS): 16

3. Kariv R(PI), Enden A(T), Zvibel I(PI), Rosner G(C), Brill S(C), Halpern Z(C), Oren R(PI), 2003 .
Triiothyronine and interleukin 6 (IL-6) induce expression of HGF in an immortalized hepatic stellate cell line .
Liver International 23:187, 2003 .
(Impact Factor 3.870; Rank 16/74-Gastroenterology). Citations (WOS): 12

4. Gur E(PI), Deckel R(C), Zvibel I(C), Brazovsky E(C), Kariv R(C), Brill S(C), Halpern Z(C), Oren R(PI*),
2003 .
A novel method for liver repopulation: Hetero grafting of micro-liver slices in a rat model .
Liver transplantation 2003, 9(4): 421-4 .
(Impact Factor 3.944; Rank 15/74-Gastroenterology; Rank 11/198-Surgery; Rank 5/26-Transplantation). Citations (WOS): 2

5. Zvibel I(PI), Brill S(PI), Kariv R(C), Golan T(S), Chebath J(C), Halpern Z(C), Ravel M(C), Oren R(C) . Chimeric Molecule IL-6/Soluble IL-6 Receptor Is a Potent Mitogen for Fetal Hepatocytes .
J Cell Physiol. 2004 Aug;200(2):245-52 .
(Impact Factor 4.218; Rank 13/79-Physiology; 63/184 Cell Biology). Citations (WOS): 4

6. Strul H(PI), Liberman E(C), Kariv R(C), Gartner M(C), Kazanov D(T), Keidar A(C), Carmeli Y(C), Degani Y(T), Halpern Z(C), Arber N(PI) .
Prospective assessment of microsatellite instability in gastrointestinal neoplasia in Ashkenazi and non-Ashkenazi Jews .
J Med. 2003;34(1-6):139-48 .

7. Strul H(PI), Barenboim E(C), Leshno M(C), Kariv R(C), Eljadeff E(C), Eljadeff Y(C), Gartner M(C), Kazanov D(T), Strier L(C), Keidar A(C), Knaani Y(T), Degani Y(T), Sobol-Drori H(C), Halpern Z(C) and Arbrer N(C) . The I1307K adenomatous polyposis coli gene variant does not contribute in the assessment of the risk for colorectal cancer in Ashkenazi Jews .
Cancer Epidemiology Biomarkers and Prevention. 2003 Oct;12(10):1012-5. (Impact Factor 4.559; Rank 39/196Oncology;Rank 10/158-Public, Environmental & Occupational Health). Citations (WOS): 14

8. Hana Strul(PI), Revital Kariv(CO-PI), Moshe Leshno(C), Aharon Halak(C), Markus Jakubowicz(C), Moshe Santo(C), Mark Umansky(C), Hain Shirin(C), Yaára Degani(C), Miri Revivo(T), Zamir Halpern(C), Nadir Arber(C) . The Prevalence Rate and Anatomic Location of Colorectal Adenoma and Cancer Detected by Colonoscoppy in Average-Risk Individuals Aged 40-80 years .
Am J Gastroenterol. 2006 Feb;101(2):255-62.
(Impact Factor 7.553; Rank 7/74-Gastroenterology). Citations (WOS): 73

9. Revital Kariv(PI), Elisa Tiomny(C), Roman Grenshpon(C), Roy Dekel(C), Galit Waisman(T), Yehuda Ringel(C) and Zamir Halpern(C) .
Low-dose Naltrexone for the Treatment of Irritable Bowel Syndrome- A pilot study .
Digestive Diseases and Sciences. 2006 .
(Impact Factor 2.260; Rank 36/74-Gastroenterology). Citations (WOS): 9

10. Revital Kariv,(PI) Moshe Leshno,(C) Anat Beth-Or,(C), Hana Strul,(C) Laurie Blendis, (C) Ehud Kokia, (C)
Dina Noff,(C) Shira Zelber-Sagie, RD(C) Bracha Sheinberg, (C) Ran Oren,(C) Zamir Halpern.(C)
Re-evaluation of serum Alanine aminotransferase upper normal limit and its modulating factors in a large-scale population study .
Liver International 2006 May;26(4):445-50.
(Impact Factor 3.870; Rank 16/74-Gastroenterology). Citations (WOS): 49

11. Shen B (PI), Plesec T (C), Remzi FH (C), Kariv R (C), Lopez R (C), Queener E (T), Fazio VW,(C), Goldblum JR (C) .
Evaluation of tissue eosinophilia in the pouch and afferent limb in patients with restorative proctocolectomy .
Inflamm Bowel Dis. 2008 Jun;14(6):744-9.
(Impact Factor 5.119; Rank 11/74-Gastroenterology and Hepatology) Citations (WOS):2

12. Kariv Y,(PI), Kariv R,(C), Hammel JP,(C), Lavery IC,(C) .
Postoperative radiotherapy for stage IIIA rectal cancer: is it justified ?
Dis Colon Rectum. 2008 Oct;51(10):1459-66 .
(Impact Factor 3.336; Gastroenterology & Hepatology 21/74;Rank 18/198-Surgery). Citations (WOS): 3

13. Revital Kariv(PI), M.D. Thomas P Plesec(C), M.D. Mary P Bronner(C), M.D, John R Goldblum(C), M.D, Mary Oldenburgh(T), RN, Thomas W Rice, M.D. (C), Gary W Falk(C), M.D, M.S .
The “Seattle Protocol” for High-Grade Dysplasia in Barrett’s Esophagus Still Misses Unsuspected Cancer at Esophagectomy
Clinical Gastroenterology and Hepatology. Clin Gastroenterol Hepatol. 2008 Dec 13 .
(Impact Factor 6.648; Rank 8/74-Gastroenterology and Hepatology). Citations (WOS): 16

14. Goldberg Y(PI), Porat RM(C), Kedar I(C), Shochat C(C), Galinsky D(C), Hamburger T(T), Hubert A(C), Strul H(C), Kariiv R(C), Ben-Avi L(C), Savion M(C), Pikarsky E(C), Abeliovich D(C), Bercovich D(C), Lerer I(C), Peretz T(C) .
An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC.
Fam Cancer. 2010 Jun;9(2):141-50.
(Impact Factor 1.935; Rank 111/161 -Genetics & Heredity; 133/197- Oncology) Citations (WOS): 2

15. Kariv R(PI),, Plesec TP(C),, Gaffney K(C),, Lian L(S),, Fazio VW(C),, Remzi FH(C),, Lopez R(C),,
Goldblum JR(C),, Shen B(C) .,
Pyloric gland metaplasia and pouchitis in patients with ileal pouch-anal anastomoses .
Aliment Pharmacol Ther. 2010 Jan 27. ( Impact Factor 4.548; Rank 12/74 - Gastroenterology and Hepatology; 32/260- Pharmacology & Pharmacy). Citations (WOS): 4

16. Kariv R(PI),, Remzi FH(C),, Lian L(S),, Bennett AE(C),, Kariv Y(C),, Fazio VW(C),, Lavery IC(C),, Shen
B(C). ,
Preoperative Colorectal Neoplasia Increases the Risk for Pouch Neoplasia in Patients with Restorative Proctocolectomy .
Gastroenterology. 2010 Sep;139(3):806-12, 812.e1-2. Epub 2010 Jun 9. (Impact Factor 12.821; Rank 1/74 - Gastroenterology and Hepatology), Citations (WOS): 23

17. Shlomai A(PI), Kariv R(C), Leshno M(C), Beth-or A(C), Sheinberg B(C), Halpern Z(C) .
Large-scale population analysis reveals an extremely low threshold for "non-healthy" alanine aminotransferase that predicts diabetes mellitus .
J Gastroenterol Hepatol. 2010 Oct;25(10):1687-91. (Impact Factor 3.325; Rank 22/74- Gastroenterology and Hepatology), Citations (WOS): 5

18. Rosner G(PI), Paul R(C), Bercovich D(C), Shochat C(C), Solar I(C), Strul H(C), Kariv R(C), Halpern Z(C). A protocol for genetic evaluation of patients with multiple colorectal adenomas and without evidence of APC gene mutation.Isr Med Assoc J. 2010 Sep;12(9):549-53.
(Impact Factor 0.978; Rank 80/151 - Medicine, General & Internal). Citations (WOS): 3

19. Kariv R(PI), Navaneethan U(C), Venkatesh PG, (C) Lopez R(C), Shen B(C),. Impact of Clostridium difficile infection in patients with ulcerative colitis .
J Crohns Colitis. 2011 Feb;5(1):34-40. Epub 2010 Oct 30 .
(Impact Factor 3.385; Rank 20/74- Gastroenterology and Hepatology). Citations (WOS): 0 Reply. Kariv R(PI), Shen B(C) .
Gastroenterology. 2011 Jan 25. (Impact Factor 12.821; Rank 1/74-Gastroenterology and Hepatology), Citations
(WOS): 0

20. Emmanuel C. Obusez(S), Lei Lian(C), Revital Kariv(C), Carol Burke(C), and Bo Shen(PI), MD .
DIAGNOSTIC YIELD OF COLONOSCOPY FOR CONSTIPATION AS A SOLE INDICATION .
Colorectal Dis. 2011 May 12 .
(Impact Factor 2.081; Rank 43/74 - Gastroenterology and Hepatology), Citations (WOS):1 .

21. Zvibel I(C), Wagner A(S), Pasmanik-Chor M(C), Varol C(C), Oron-Karni V(C), Santo EM(C), Halpern Z(C),
Kariv R(PI) .
Transcriptional profiling identifies genes induced by hepatocyte-derived extracellular matrix in metastatic human colorectal cancer cell lines .
Clin Exp Metastasis. 2013 Feb;30(2):189-200. doi: 10.1007/s10585-012-9527-8. Epub 2012 Aug 29 .
Clin Exp Metastasis ..
(IF 3.460; Rank 71/196-Oncology). Citations(WOS):1

22. Bronner K (S), Mesters I(C), Weiss-Meilnik A(C), Geva R(C), Rozner G(C), Strul H(C), Inbar M(C), Halpern Z(C), Kariv R(PI) .
Do individuals with a family history of colorectal cancer adhere to medical recommendations for the prevention of colorectal cancer?
Fam Cancer. 2013 Apr 2 .
(Impact Factor 1.935; Rank 111/161 -Genetics & Heredity; 133/197- Oncology) Citations (WOS): 1 .

23. Bronner K(S), Mesters I(C), Weiss-Meilnik A(C), Geva R(C), Rozner G(C), Strul H(C), Inbar M(C), Halpern Z(C), Kariv R(PI) .
Determinants of adherence to screening by colonoscopy in individuals with a family history of colorectal cancer .
Patient Educ Couns. 2013 Aug 2. pii: S0738-3991(13)00274-7. doi: 10.1016/j.pec.2013.06.029 .
(IF 2.372;Rank 126/161--Public,Environmental & Occupational Health)

24. Sebastian S(C), Hernández V(C), Myrelid P(C), Kariv R(C), Tsianos E(C), Toruner M(C), Marti-Gallostra M(C), Spinelli A(C), van der Meulen-de Jong AE(C), Yuksel ES(C), Gasche C(C), Ardizzone S(C), Danese S(PI)
Colorectal cancer in inflammatory bowel disease: Results of the 3rd ECCO pathogenesis scientific workshop (I) .
J Crohns Colitis. 2013 May 9. pii: S1873-9946(13)00147-5. doi: 10.1016/j.crohns.2013.04.008. [Epub ahead of print]
(IF 3.385;Rank 20/74-Gastroenterology&Hepatology)

25. Goldberg Y(PI), Kedar I(PI), Kariiv R(PI), Halpern N(C), Plesser M(C), Hubert A(C), Kaduri L(C), Sagi M(C), Lerer I(C), Abeliovich D(C), Hamburger T(C), Nissan A(C), Goldshmidt H(C), Solar I(C), Geva R(C), Strul H(C), Rosner G(C), Baris H(C), Levi Z(C), Peretz T(C) .
Lynch Syndrome in high risk Ashkenazi Jews in Israel .
Fam Cancer. 2013 Aug 30 .
(Impact Factor 1.935; Rank 111/161 -Genetics & Heredity; 133/197- Oncology) Citations (WOS): 1 .



26. Goldstein AL(PI), Kariv R(PI), Klausner JM(C), Tulchinsky H(PI) .
Patterns of Adenoma Recurrence in Familial Adenomatous Polyposis Patients after Ileal Pouch-Anal Anastomosis . Dig Surg. 2015;32(6):421-5 .
IF 1.664; SURGERY 103/197 – Q3; Cited: 1 .

27. Rex DK(PI), Adler SN(C), Aisenberg J(C), Burch WC Jr(C), Carretero C(C), Chowers Y(C), Fein SA(C),
Fern SE(C), Fernandez-Urien Sainz I(C), Fich A(C), Gal E(C), Horlander JC Sr(C), Isaacs KL(C), Kariv R(C), Lahat A(C), Leung WK(C), Malik PR(C), Morgan D(C), Papageorgiou N(C), Romeo DP(C), Shah SS(C), Waterman M(PI) .
Accuracy of capsule colonoscopy in detecting colorectal polyps in a screening population .
Gastroenterology. 2015;148(5):948-57.e2.
IF 18.392; GASTROENTEROLOGY & HEPATOLOGY 1/79 – Q1 ;
Cited: 43 .

28. Goldberg Y(PI), Barnes-Kedar I(C), Lerer I(C), Halpern N(C), Plesser M(C), Hubert A(C), Kadouri L(C), Goldshmidt H(C), Solar I(C), Strul H(C), Rosner G(C), Baris HN(C), Peretz T(C), Levi Z(PI), Kariv R(PI). Genetic features of Lynch syndrome in the Israeli population .
Clin Genet. 2015;87(6):549-53 .
IF 3.326; GENETICS & HEREDITY 62/167- Q2; Cited: 3 .

29. Rosner G(PI), Bercovich D(C), Daniel YE(C), Strul H(C), Fliss-Isakov N(C), Ben-Yehoiada M(C), Santo E(C), Halpern Z(C), Kariv R(PI) .
Increased risk for colorectal adenomas and cancer in mono-allelic MUTYH mutation carriers: results from a cohort of North-African Jews .
Fam Cancer. 2015;14(3):427-36 .
IF 1.66; GENETICS & HEREDITY 120/167 – Q3; Cited: 2 .

30. Vavricka SR(PI), Greuter T(C), Scharl M(C), Mantzaris G(C), Shitrit AB(C), Filip R(C), Karmiris K(C), Thoeringer CK(C), Boldys H(C), Wewer AV(C), Yanai H(C), Flores C(C), Schmidt C(C), Kariv R(C), Rogler G(C), Rahier JF(PI); ECCO CONFER investigators .
Cogan’s Syndrome in Patients With Inflammatory Bowel Disease--A Case Series .
J Crohns Colitis. 2015;9(10):886-90.
IF 5.813; GASTROENTEROLOGY & HEPATOLOGY 12/79 – Q1; Cited: 6 .

31. Fink SP(PI), Myeroff LL(C), Kariv R(C), Platzer P(C), Xin B(C), Mikkola D(C), Lawrence E(C), Morris N(C), Nosrati A(C), Willson JK(C), Willis J(C), Veigl M(C), Barnholtz-Sloan JS(C), Wang Z(C), Markowitz SD(PI) . Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival .
Oncotarget. 2015;6(31):30500-15 .
IF 5.168; ONCOLOGY 44/217 – Q1; Cited: 11 .

32. Levi Z(PI), Kariv R(PI), Barnes-Kedar I, Goldberg Y(C), Half E(C), Morgentern S(C), Eli B(C), Baris HN(C), Vilkin A(C), Belfer RG(C), Niv Y(C), Elhasid R(C), Dvir R(C), Abu-Freha N(C), Cohen S(PI) .
The gastrointestinal manifestation of constitutional mismatch repair deficiency syndrome: from a single adenoma to polyposis-like phenotype and early onset cancer .
Clin Genet. 2015;88(5):474-8 .
IF 3.326; GENETICS & HEREDITY 62/167 – Q2; Cited: 9 .

33. Aronson M, Gallinger S(C), Cohen Z(C), Cohen S(C), Dvir R(C), Elhasid R(C), Baris HN(C), Kariv R(C),
Druker H(C), Chan H(C), Ling SC(C), Kortan P(C), Holter S(C), Semotiuk K(C), Malkin D(C), Farah R(C), Sayad
A(C), Heald B(C), Kalady MF(C), Penney LS(C), Rideout AL(C), Rashid M(C), Hasadsri L(C), Pichurin P(C), RiegertJohnson D(C), Campbell B(C), Bakry D(C), Al-Rimawi H(C), Alharbi QK(C), Alharbi M(C), Shamvil A(C), Tabori U(PI), Durno C(PI) .
Gastrointestinal Findings in the Largest Series of Patients With Hereditary Biallelic Mismatch Repair Deficiency Syndrome: Report from the International Consortium .
Am J Gastroenterol. 2016;111(2):275-84.
IF 9.566; GASTROENTEROLOGY & HEPATOLOGY 6/79 – Q1; Cited: 11 .

34. Baris HN(PI), Barnes-Kedar I(C), Toledano H(C), Halpern M(C), Hershkovitz D(C), Lossos A(C), Lerer I,
Peretz T, Kariv R, Cohen S, Half EE, Magal N, Drasinover V, Wimmer K, Goldberg Y(C), Bercovich D(C), Levi Z(PI) . Constitutional Mismatch Repair Deficiency in Israel: High Proportion of Founder Mutations in MMR Genes and Consanguinity .
Pediatr Blood Cancer. 2016;63(3):418-27.
IF 2.513; PEDIATRICS 26/121 – Q1; Cited: 4 .

35. Caspi M(PI), Firsow A(C), Rajkumar R(C), Skalka N(C), Moshkovitz I(C), Munitz A(C), Pasmanik-Chor M(C), Greif H(C), Megido D(C), Kariv R(C), Rosenberg DW(C), Rosin-Arbesfeld R(PI) .
A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents .
J Mol Med. 2016;94(4):469-82.
IF 4.686; GENETICS & HEREDITY 27/167 – Q1; Cited: 2 .

36. Yedid N(S), Kalma Y(C), Malcov M(C), Amit A(C), Kariv R(C), Caspi M(C), Rosin-Arbesfeld R(C), BenYosef D(PI) .
The effect of a germline mutation in the APC gene on β-catenin in human embryonic stem cells .
BMC Cancer. 2016;16(1):952 .
IF 3.288; ONCOLGY 93/217 – Q2; Cited: 1 .

37. Kinar Y(PI), Akiva P(C), Choman E(C), Kariv R(C), Shalev V(C), Levin B(C), Narod SA(C), Goshen R(PI) . Performance analysis of a machine learning flagging system used to identify a group of individuals at a high risk for colorectal cancer .
PLoS ONE. 2017;12(2):e0171759 .
IF 2.806; MULTDISCIPLINARY SCIENCES 15/64 – Q1; Cited: 1 .

38. Goshen R(PI), Mizrahi B(C), Akiva P(C), Kinar Y(C), Choman E(C), Shalev V(C), Sopik V(C), Kariv R(C), Narod SA(PI) .
Predicting the presence of colon cancer in members of a health maintenance organisation by evaluating analytes from standard laboratory records .
Br J Cancer. 2017;116(7):944-50 .
IF 6.176; ONCOLGY 32/217 – Q1; Cited: 0 .

39. Fliss-Isakov N(S), Zelber-Sagi S(PI), Webb M, Halpern Z(C), Shibolet O, Kariv R(PI) .
Distinct Metabolic Profiles are Associated with Colorectal Adenomas and Serrated Polyps .
Obesity (Silver Spring). 2017;25 Suppl 2:S72-80 .
IF 3.873; NUTRITION & DIETETICS 18/81 – Q1; Cited: 2 .

40. Kariv R(PI), Rosner G(C), Fliss-Isakov N(C), Gluck N(C), Goldstein A(C), Tulchinsky H(C), Zelber-Sagi S(PI) .
Genotype-Phenotype Associations of APC Mutations With Pouch Adenoma in Patients With Familial Adenomatous Polyposis .
J Clin Gastroenterol. November 2017.
IF 3.328; GASTROENTEROLOGY & HEPATOLOGY 31/79 – Q2; Cited: 0 .

41. Fliss-Isakov N(S), Zelber-Sagi S(PI), Webb M(C), Halpern Z(C), Kariv R(PI) .
Smoking Habits are Strongly Associated With Colorectal Polyps in a Population-based Case-control Study .
J Clin Gastroenterol. November 2017.
IF 3.328; GASTROENTEROLOGY & HEPATOLOGY 31/79 – Q2; Cited: 0 .

42. Mlynarsky L(C), Zelber-Sagi S(C), Miller E(C), Kariv R(PI) .
Endoscopic resection of large colorectal adenomas - clinical experience of a tertiary referral centre .
Colorectal Dis. 2018;20(5):391-8 .
IF 2.689; SURGERY 56/197 – Q2; Cited: 0 .

43. Zelber-Sagi S(PI)., Ivancovsky-Wajcman D(S), Fliss Isakov N(C), Webb M(C), Orenstein D(S), Shibolet O(C), Kariv R(PI) ..
High red and processed meat consumption is associated with non-alcoholic fatty liver disease and insulin resistance .
J Hepatol. 2018;68(6):1239-46 .
IF 12.486; GASTROENTEROLOGY & HEPATOLOGY 5/79 – Q1; Cited: 0 .

44. Rosner G(PI), Gluck N(C), Bercovich D(C), Fliss-Issakov N(C), Ben-Yehoyada M(C), Aharon-Caspi S(C), Kellerman E(C), Strul H(C), Halpern Z(C) Santo E(C), Kariv R(PI) .
Novel POLD1 and POLE Gene Mutations: New players in Early-Onset Colorectal Cancer and Multiple Colorectal Adenomas .
Dis Colon Rectum. Dis Colon Rectum. 2018 Sep;61(9):1073-1079 . IF 3.519; SURGERY 32/197 – Q1; Cited: 0 .

45. Fliss-Isakov N(S)*, Kariv R(PI)*, Webb M(C), Ivancovsky D(S), Orenstein-Margalit D(S), Zelber-Sagi S(PI). *Equal Contribution .
The Mediterranean dietary pattern and its components are inversely associated with advanced colorectal polyps.World J Gastroenterol. 2018 Jun 28;24(24):2617-2627.
IF 3.365; GASTROENTEROLOGY & HEPATOLOGY 30/79 – Q2; Cited: 0 .

46. Nir Bar MD(C), Naama Schwartz(C), Michal Nissim(C), Naomi Fliss-Isacov PhD(C), Shira zelber-sagi PhD(C) Revital Kariv MD (PI)- Barrett's Esophagus with High Grade Dysplasia is Associated with a Higher Lifetime risk for non- sophageal Cancer. World J Gastroenterol. 2018 Oct 21;24(39):4472-4481. IF 3.365; GASTROENTEROLOGY & HEPATOLOGY 30/79 – Q2; Cited: 0. (updated 4/3/10)

47. Goshen R, Choman E, Ran A, Muller E, Kariv R, Chodick G, Ash N, Narod S, Shalev V. ComputerAssisted Flagging of Individuals at High Risk of Colorectal Cancer in a Large Health Maintenance Organization Using the ColonFlag Test. JCO Clin Cancer Inform. 2018 Dec;2:1-8. (New ASCO journal, no IF yet, does not appear on JCR) (updated 4/3/10)

48. Kariv R, Turner D, Rosenblum J, Morad V, Zigman N, Friedman M, Focht G, Leder O, Avitzour M, Goren I.
ESTABLISHING A REGISTRY FOR INFLAMMATORY BOWEL DISEASE PATIENTS IN MACCABI HEALTHCARE
SERVICES - JOINT PROJECT BETWEEN HOSPITALS, EPI-IIRN GROUP AND COMMUNITY
MEDICINE.Harefuah. 2018 Oct;157(10):655-659. No IF (updated 4/3/10)

49. Gilad O, Rosner G, Fliss-Isakov N, Aharon-Kaspi S, Strul H, Gluck N, Kariv R Clinical and Histologic
Overlap and Distinction Among Various Hamartomatous Polyposis Syndromes. Clin Transl Gastroenterol. 2019 May 22;10(5):1-9

50. Ivancovsky-Wajcman D, Zelber-Sagi S, Fliss Isakov N, Webb M, Zemel M, Shibolet O, Kariv R Serum Soluble Receptor for AGE (sRAGE) Levels Are Associated With Unhealthy Lifestyle and Nonalcoholic Fatty Liver Disease. Clin Transl Gastroenterol. 2019 May 22;10(5):1-10 .

51. Ivancovsky-Wajcman D, Fliss-Isakov N, Salomone F, Webb M, Shibolet O, Kariv R, Zelber-Sagi S. Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease. Dig Liver Dis. 2019 Jul 4 .

52. Margalit S, Avraham S, Shahal T, Michaeli Y, Gilat N, Magod P, Caspi M, Loewenstein S, Lahat G,
Friedmann-Morvinski D, Kariv R, Rosin-Arbesfeld R, Zirkin S, Ebenstein Y. 5-Hydroxymethylcytosine as a clinical biomarker: Fluorescence-based assay for high-throughput epigenetic quantification in human tissues.Int J Cancer. 2019 Jun 18 .

53. Kariv R, Caspi M, Fliss-Isakov N, Shorer Y, Shor Y, Rosner G, Brazowski E, Beer G, Cohen S, RosinArbesfeld R. Resorting the function of the colorectal cancer (CRC) gate keeper adenomatous Polyposis Coli (APC).Int J Cancer. 2019 Jul 8 .

54. Naomi Fliss-Isakov1,2* RD, PhD, Revital Kariv 1,2* MD, Muriel Webb1,2 MD, Dana Ivancovsky3 Msc, Dana Margalit3 Msc, Shira Zelber-Sagi1,3 RD, PhD. A healthy lifestyle pattern has a protective association with colorectal polyps. *The first and the second authors equally contributed to the paper. Eur J Clin Nutr. 2019 Jul 30 .

55. Fliss-Isakov N, Grosso G, Salomone F, Godos J, Gavalno F, Ivancovsky-Wajcman D, Shibolet O, Kariv R, Zelber-Sagi S. High Intake of Phenolic Acid Is Associated With Reduced Risk of Colorectal Adenomas Among Smokers. Clin Gastroenterol Hepatol. 2019 Aug 29 *Authors share co-last authorship .

56. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A, Lopez-Köstner F, Gluck N, Katz LH, Heinimann K, Vaccaro CA, Büttner R, Görgens H, Holinski-Feder E, Morak M,
Holzapfel S, Hüneburg R, Knebel Doeberitz MV, Loeffler M, Rahner N, Schackert HK, Steinke-Lange V, Schmiegel
W, Vangala D, Pylvänäinen K, Renkonen-Sinisalo L, Hopper JL, Win AK, Haile RW, Lindor NM, Gallinger S, Le
Marchand L, Newcomb PA, Figueiredo JC, Thibodeau SN, Wadt K, Therkildsen C, Okkels H, Ketabi Z, Moreira L,
Sánchez A, Serra-Burriel M, Pineda M, Navarro M, Blanco I, Green K, Lalloo F, Crosbie EJ, Hill J, Denton OG,
Frayling IM, Rødland EA, Vasen H, Mints M, Neffa F, Esperon P, Alvarez K, Kariv R, Rosner G, Pinero TA, Gonzalez ML, Kalfayan P, Tjandra D, Winship IM, Macrae F, Möslein G, Mecklin JP, Nielsen M, Møller P. Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database. Genet Med. 2019 Jul 24 .

57. Salomone F, Ivancovsky-Wajcman D, Fliss-Isakov N, Webb M, Grosso G, Godos J, Galvano F, Shibolet O, Kariv R, Zelber-Sagi S. Higher phenolic acid intake independently associates with lower prevalence of insulin resistance and non-alcoholic fatty liver disease. JHEP Rep. 2020 Jan 28;2(2):100069 .

58. Greenberg A, Kariv R, Solar I, Hershkovitz D.Geographic Heterogeneity for Mismatch Repair Proteins Is Associated with Defects in DNA Repair. Isr Med Assoc J. 2020 Jan;22(1):32-36.

59. Dahary D, Golan Y, Mazor Y, Zelig O, Barshir R, Twik M, Iny Stein T, Rosner G, Kariv R, Chen F, Zhang Q, Shen Y, Safran M, Lancet D, Fishilevich S.Genome analysis and knowledge-driven variant interpretation with TGex. BMC Med Genomics. 2019 Dec 30;12(1):200. doi: 10.1186/s12920-019-0647-8.

60. Increased incidence of coeliac disease autoimmunity rate in Israel: a 9-year analysis of population-based data.
Lechtman N, Shamir R, Cohen S, Chodick G, Kariv R, Supino-Rosin L, Weintraub Y, Yerushalmy-Feler A, Ben Tov
A. Aliment Pharmacol Ther. 2021 Mar;53(6):696-703. doi: 10.1111/apt.16282. Epub 2021 Feb 5. PMID: 33547687
61. Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report.
Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Nakken S, Hovig
E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K,
Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W, Vangala D, Perne C, Strauß HG, Tecklenburg J, Holinski-Feder
E, Steinke-Lange V, Mecklin JP, Plazzer JP, Pineda M, Navarro M, Vidal JB, Kariv R, Rosner G, Piñero TA,
Gonzalez ML, Kalfayan P, Ryan N, Ten Broeke SW, Jenkins MA, Sunde L, Bernstein I, Burn J, Greenblatt M, de Vos
Tot Nederveen Cappel WH, Della Valle A, Lopez-Koestner F, Alvarez K, Büttner R, Görgens H, Morak M, Holzapfel
S, Hüneburg R, von Knebel Doeberitz M, Loeffler M, Rahner N, Weitz J, Pylvänäinen K, Renkonen-Sinisalo L,
Lepistö A, Auranen A, Hopper JL, Win AK, Haile RW, Lindor NM, Gallinger S, Le Marchand L, Newcomb PA, Figueiredo JC, Thibodeau SN, Therkildsen C, Okkels H, Ketabi Z, Denton OG, Rødland EA, Vasen H, Neffa F,
Esperon P, Tjandra D, Möslein G, Sampson JR, Evans DG, Seppälä TT, Møller P. Genet Med. 2020 Dec 1. doi: 10.1038/s41436-020-01029-1. Online ahead of print. PMID: 33257847

62. Ultra-Processed Food Intake and Smoking Interact in Relation with Colorectal Adenomas.
Fliss-Isakov N, Zelber-Sagi S, Ivancovsky-Wajcman D, Shibolet O, Kariv R. Nutrients. 2020 Nov 14;12(11):3507.

63. Determinants of Pouch-Related Symptoms, a Common Outcome of Patients With Adenomatous Polyposis Undergoing Ileoanal Pouch Surgery.
Gilad O, Gluck N, Brazowski E, Kariv R, Rosner G, Strul H. Clin Transl Gastroenterol. 2020 Oct;11(10):e00245.
64. Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum.
Dominguez-Valentin M, Sampson JR, Møller P, Seppälä TT; PLSD Collaborators. Int J Cancer. 2021 Jan 15;148(2):512-513. doi: 10.1002/ijc.33214. Epub 2020 Jul 30. PMID: 32783184 No abstract available.

65. Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database.
Dominguez-Valentin M, Seppälä TT, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen
M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro
CA, Green K, Lalloo F, Hill J, Schmiegel W, Vangala D, Perne C, Strauß HG, Tecklenburg J, Holinski-Feder E, Steinke-Lange V, Mecklin JP, Plazzer JP, Pineda M, Navarro M, Vidal JB, Kariv R, Rosner G, Piñero TA, Gonzalez ML, Kalfayan P, Sampson JR, Ryan NAJ, Evans DG, Møller P, Crosbie EJ. J Clin Med. 2020 Jul 18;9(7):2290. doi:
10.3390/jcm9072290. PMID: 32708519 Free PMC article.

66.Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.
Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins
MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot
Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A, Lopez-
Köstner F, Gluck N, Katz LH, Heinimann K, Vaccaro CA, Büttner R, Görgens H, Holinski-Feder E, Morak M,
Holzapfel S, Hüneburg R, Knebel Doeberitz MV, Loeffler M, Rahner N, Schackert HK, Steinke-Lange V, Schmiegel
W, Vangala D, Pylvänäinen K, Renkonen-Sinisalo L, Hopper JL, Win AK, Haile RW, Lindor NM, Gallinger S, Le
Marchand L, Newcomb PA, Figueiredo JC, Thibodeau SN, Wadt K, Therkildsen C, Okkels H, Ketabi Z, Moreira L,
Sánchez A, Serra-Burriel M, Pineda M, Navarro M, Blanco I, Green K, Lalloo F, Crosbie EJ, Hill J, Denton OG,
Frayling IM, Rødland EA, Vasen H, Mints M, Neffa F, Esperon P, Alvarez K, Kariv R, Rosner G, Pinero TA, Gonzalez ML, Kalfayan P, Tjandra D, Winship IM, Macrae F, Möslein G, Mecklin JP, Nielsen M, Møller P. Genet Med. 2020 Sep;22(9):1569. doi: 10.1038/s41436-020-0892-4. PMID: 32690931 Free PMC article.

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